REALQUALITY ASPERGILLUS

The REALQUALITY Aspergillus kit is indicated for qualitative DNA detection of the DNA of Aspergillus fumigatus, Aspergillus terreus and Aspergillus spp. by Real-Time PCR.

Product Characteristics

• The device is validated on DNA extracted from various samples types
• The assay requires only 5 µL of DNA extracted
• The assay includes dUTP/UNG system for preventing carry-over contamination and a fluorescence normalizer
• The automatic format of the assay can be used on GENEQUALITY^® automatic platforms
• Easy interpretation of results with AB Genius Report software

Kit content

• Ready-to-use reagents for Real-Time PCR 
• Internal control 
• Positive control

Further Information

The Aspergillus genus includes ubiquitous filamentous fungi commonly present in various environments, both outdoors and indoors. Of the over 250 known Aspergillus species, fewer than 40 are of clinical interest. The main route of infection in humans occurs through inhalation of spores produced by the fungus. Allergic bronchopulmonary aspergillosis and chronic pulmonary aspergillosis are the most common infections caused by this pathogen and mainly affect patients with asthma or cystic fibrosis. Invasive aspergillosis, less frequent, is found in immunocompromised patients and can lead to infections with high mortality and morbidity rates. Treatment varies depending on the type of aspergillosis and may include the use of antifungal drugs or the need for surgery.

The main etiological agent of aspergillosis is Aspergillus fumigatus. However, other Aspergillus species are emerging as pathogens that can also cause severe invasive infections, including A. terreus, which is particularly resistant to antifungals used in aspergillosis therapies, as well as A. flavus, A. glaucus, A. nidulans, A. niger, and A. ustus. A rapid, accurate and reliable diagnosis is essential for an appropriate treatment plan, allowing to reduce the time spent in intensive care units and increase survival rates.

Ordering Information